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Effects of carbon nanotubes on human monocytes

TitoloEffects of carbon nanotubes on human monocytes
Tipo di pubblicazioneArticolo su Rivista peer-reviewed
Anno di Pubblicazione2009
AutoriDe Nicola, M., Nuccitelli S., Mirabile Gattia Daniele, Traversa E., Magrini A., Bergamaschi A., and Ghibelli L.
RivistaAnnals of the New York Academy of Sciences
Volume1171
Paginazione600-605
ISBN Number9781573317375
ISSN00778923
Parole chiaveantineoplastic activity, Antineoplastic Agents, Apoptosis, carbon, Cell Count, cell death, cell viability, conference paper, controlled study, Cytotoxicity, Cytotoxins, dose time effect relation, Dose-Response Relationship, Drug, drug potentiation, etoposide, Flow cytometry, human, human cell, Humans, Leukocytes, monocyte, Monocytes, Mononuclear, mononuclear cell, multi walled nanotube, Nanotubes, Necrosis, normal human, Phytogenic, Risk assessment
Abstract

Carbon nanotubes are considered to be one of the novel most attractive materials in nanotechnology. Because of their multiple industrial and biomedical applications, thorough studies on their toxicity and biocompatibility become a priority in order to prevent possible health risks. In this study the effects of multiwalled carbon nanotubes (MWCNT) on healthy monocytes from human peripheral blood were investigated. The results indicate that MWCNT exert a cytotoxic effect on monocytes, inducing cell death and increasing the extent of apoptosis induced by a chemotherapic agent. This cytotoxic effect may have important implications, and much attention in terms of evaluation of exposure risks is recommended. © 2009 New York Academy of Sciences.

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cited By 10

URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-69149098836&doi=10.1111%2fj.1749-6632.2009.04892.x&partnerID=40&md5=5b557de304d89fd2aec403eae1429982
DOI10.1111/j.1749-6632.2009.04892.x
Citation KeyDeNicola2009600